Tsukishima is a really chill villain, and he gives off a very relaxed aura, somewhat like how Aizen was in the beginning. His abilities are putting Ichigo in a really tight pickle that has frozen him psychologically, and he ends up being unable to do anything besides desperately trying to kill Tsukishima. Ichigo manages to cut off his arm, but Tsukishima doesn’t even seem like he’s in pain, just mildly shocked. Everyone honestly believes that Ichigo is crazy, and for the first time his friends are not on his side and are appalled by his violent behavior. Now he has to face off against Inoue and Chad, and is stuck in a pretty bad situation. Running off is also becoming less of an option, but if hundreds of Bleach chapters have told me anything, Ichigo would never attack them even if just to knock them out temporarily.
Inoue will probably heal Tsukishima too, and there is little Ichigo’s spiderman/power ranger suit can do. If combat is out of the question, Ichigo and Ginjou could try to convince the others that their memories have been tainted, perhaps by proving some discrepancies. I don’t see any ill will from Tsukishima yet though, aside from using Ichigo’s friends as human shields. He just seems to be interested in Ichigo like Aizen was, and hasn’t made an unprovoked attack on him yet; so far Ichigo has made the first strike each time. I’m still somewhat suspicious of Ginjou too, and he could easily have a hidden agenda and probably knows more than he’s revealing.